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What is Evamist?
During menopause, your body produces less estrogen, causing many of the symptoms associated with menopause.1 Evamist uses
17ß-estradiol, an estrogen chemically synthesized from a plant source.2
This does not mean Evamist is safer or more effective than other hormone therapies. Evamist is the only estrogen therapy spray approved by the FDA.

Evamist (estradiol transdermal spray) has been proven to reduce moderate to severe hot flashes caused by menopause. It has been shown to reduce both the severity and frequency of hot flashes—all in a low dose of estrogen.3 Doctors agree that hormone therapy should always be used at the lowest effective dose.1

Though there are other products that contain estradiol, only Evamist is a once-daily spray. It delivers low doses of estrogen directly through the skin (transdermally) to your bloodstream.3,4
How is Evamist applied?
 
Evamist is sprayed on a small area of your arm, and
the medication is invisible and dries quickly within
two minutes. The Evamist applicator contains
56 sprays and can be used to deliver 1, 2 or 3
spray doses each day. Treatment with estrogen
should be started at the lowest dose possible, and
used only for as long as needed to provide relief of
moderate to severe hot flashes associated with menopause. Your doctor can
start you at the lowest dose (1 spray) and easily adjust your dose to 2 or 3 sprays to find the dose that works for you. Evamist is the only estrogen therapy with this kind of dosing flexibility.
 
Is Evamist right for you?
Just because your mother suffered through her menopause symptoms doesn’t mean you have to. Talk to your doctor to see if estrogen therapy with Evamist may be right for you. Many other women have experienced the benefits of using Evamist to reduce their moderate to severe hot flashes. In fact, in a survey of women taking Evamist, 100% of patients stated they would recommend Evamist to a friend.*2 Also, for women who had previously tried an estrogen patch, 3 out of 4 women reported that Evamist was more convenient than their previous patch therapy.†2

Keep in mind there are risks associated with any estrogen therapy, including Evamist. Please click here to review the most important information you need to know about Evamist.
 
Evamist spray
 
* As reported in a patient survey of 515 women using Evamist.2
As reported in an experience study of 247 women using Evamist, 53 of whom had previously used estrogen patch therapy.2
In the same patient survey, 100% of women indicated they would recommend Evamist to a friend.
» References
Important Safety Information
What is the most important information I should know about EVAMIST (an estrogen hormone)?

Using estrogen-alone may increase your chance of getting cancer of the uterus (womb). Report any unusual vaginal bleeding right away while you are using EVAMIST. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare provider should check any unusual vaginal bleeding to find the cause.

Do not use estrogen-alone to prevent heart disease, heart attacks, strokes or dementia (decline of brain function).

Using estrogen-alone may increase your chances of getting strokes or blood clots.

Using estrogen-alone may increase your chance of getting dementia, based on a study of women 65 years or older.

Do not use estrogens with progestins to prevent heart disease, heart attack or dementia.

Using estrogens with progestins may increase your chances of getting heart attacks, strokes, breast cancer, or blood clots.

Using estrogens with progestins may increase your chance of getting dementia, based on a study of women 65 years and older.

You and your healthcare provider should talk regularly about whether you still need treatment with EVAMIST.

The estrogen in EVAMIST (estradiol transdermal spray) spray can transfer from the area of skin where it was sprayed to other people. Do not allow others, especially children, to come into contact with the area of your skin where you sprayed EVAMIST. Young children who are accidentally exposed to estrogen through contact with women using EVAMIST (estradiol transdermal spray) may show signs of puberty that are not expected (for example, breast budding).


EVAMIST (estradiol transdermal spray) is an estrogen hormone used after menopause to reduce moderate to severe hot flashes.

Evamist should not be used if you have unusual vaginal bleeding; currently have or have had certain cancers, including cancer of the breast or uterus; had a stroke or heart attack year; currently have or have had blood clots; currently have or have had liver problems; have been diagnosed with a bleeding disorder; are allergic to EVAMIST or any of its ingredients; or think you may be, or know that you are, pregnant.

The most common side effects that may occur with Evamist are headache, breast pain, irregular vaginal bleeding or spotting, stomach or abdominal cramps, bloating, nausea and vomiting, hair loss, fluid retention, and vaginal yeast infection.

Please see full patient information for EVAMIST.

Please see full prescribing information for EVAMIST, including boxed warnings.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

 
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